Factors That Influence Neuroplasticity – The Case for Mashing up Brain Exercises and Psilocybin

We can influence our brain development in positive or negative directions. The more we positively engage and challenge our mind and bodies, the longer our brains function at a high level. It follows that if we use our mind and bodies in positive ways when we are microdosing with psilocybin, a period during which our brain has a high level of neuroplasticity and neurogenesis, we will achieve more in the way of long-term gains.


Brain stimulation while microdosing psilocybin produces positive and long lasting cognitive adaptations

If we do brain exercises while microdosing, there is tremendous potential for positive and lasting cognitive change. It doesn’t have ro be much; just five minutes within the first four hours after microdosing. 


The main promoter of brain plasticity is something called brain-derived neurotrophic factor (BDNF), which affects all parts of the nerve cell and is most abundant in the hippocampus and prefrontal cortex. 

BDNF increases with certain brain exercises AND is raised with psilocybin exposure so a mash-up of these two, brain exercises while under the influence of microdosing, leads to synergistic long-term benefits.


Brain Stimulation – 

BDNF rises naturally with the neuronal excitation found in activities like brain exercises, creative pursuits, physical activity, and social interaction. This leads to the formation of synapses between neurons in the nervous system, which is called synaptogenesis AND it makes those synaptic connections stronger. 

Like any other part of the body that needs to be strengthened, the brain is like a muscle. The more you exercise it, the stronger and healthier your mind becomes. 

Activities that can excite brain neurons include brain games such as chess, jigsaw puzzles, sudoku, memory games, and crosswords, as well as physical activity, social interaction, and creative pursuits. Make sure to try one of these on your next microdosing day.